Evidence Hub

Association between the PaO2 /FiO2 Ratio and Pneumonia Severity Index in Pneumonia Patients with ARDS: A Cross-sectional Study from a Critical Care Unit

R. Shah, Parth R. Shah, Trupti Jansari, Amit Chauhan

Journal of Clinical and Diagnostic Research, 2025

67 participants

Abstract

Introduction: Pneumonia is a major concern in patients in critical care units. Severe pneumonia can lead to hypoxaemia and Acute Respiratory Distress Syndrome (ARDS). The Partial pressure of arterial Oxygen (PaO2 ), Fraction of inspired Oxygen (FiO2 ) ratio and Pneumonia Severity Index (PSI) are helpful in assessing the severity of pneumonia and ARDS. Identifying the correlation between the PaO2 /FiO2 ratio and PSI can improve patient management strategies and outcomes in cases of pneumonia.

Aim: To analyse the PaO2 /FiO2 ratio and the PSI in pneumonia patients with ARDS and examine their association.

Materials and Methods: A cross-sectional study was conducted in the Critical Care Unit, Smt. B.K. Shah Medical Institute and Research Hospital, Sumandeep Vidyapeeth Deemed to be University, Piparia, Waghodia, Gujarat, India, from October 2024 to November 2024. Study involved 67 pneumonia patients with ARDS, aged over 18 years, who were admitted to the Critical Care Unit. Following informed consent, detailed history taking and clinical examinations were performed. Routine investigations, including Arterial Blood Gas (ABG), blood urea nitrogen, serum sodium, serum glucose, haematocrit and chest X-ray, were conducted. The PSI score and PaO2 /FiO2 ratio were calculated at the time of pneumonia diagnosis. Statistical tests for prevalence and associations within the data were applied, with the Chi-square test used and a p-value of less than 0.05 considered statistically significant.…

How strong is the evidence?

Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 67 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free