Bacterial profile, antimicrobial susceptibility patterns, and associated factors of community-acquired pneumonia among adult patients in south india: a cross-sectional study
Abstract
Objective: This study aimed to analyze the bacterial profile, antibiotic sensitivity patterns, and prevalence of multidrug resistance in community-acquired pneumonia patients at a tertiary care hospital in Bangalore, India.
Methods: Bacterial isolates were identified using standard microbiological techniques and their antibiotic sensitivity was determined using the Kirby-Bauer disk diffusion method.
Results: A total of 215 sputum samples were processed, of which 150 tested positive for bacteria. Klebsiella pneumoniae (32%) was the most common isolate, followed by Acinetobacter spp. (20.66%), and Pseudomonas aeruginosa (16%). Notable antibiotic resistance, particularly against third-generation cephalosporins, was observed, with 17.2% of g-negative isolates exhibiting multidrug resistance, primarily due to Extended-Spectrum Beta-Lactamase (ESBL) production.
Conclusion: These findings highlight the need for more effective empirical treatment strategies for CAP.
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.
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