Clinical and Etiological Profile of Community Acquired Pneumonia in a Tertiary Care Centre in South India – A Cross Sectional Study
Abstract
Several factors play a major role in the natural course of pneumonia unless adequately intervened and few of these include the etiological agent and the risk factors in an individual, such as age and comorbidities. This study was done at a tertiary care institution in South India with an inpatient population that comprised different regions of Kerala, a state in South India which would to an extent, be representative of the community, so as to identify the clinical and etiological profile of CAP.
Our study aimed at formulating a clinical profile, etiology, and outcome of patients with community-acquired pneumonia that required inpatient management.
The population under study included inpatients fulfilling the criteria for community-acquired pneumonia as elucidated in BTS guidelines, admitted at a tertiary care center in South India. A sample size of 160 was studied, and data related to investigations done and organisms isolated was collected retrospectively. A clinical profile was made with age, gender comorbidities, and other risk factors. Investigations ranged from sputum microscopy to the Filmarray Pneumonia panel.
Microbial etiology was confirmed in 60% of patients with nasal swabs, sputum, and BAL studies. Influenza A was detected in 69 (43%) cases, followed by Gram negative bacilli in 22 (13.75%) cases and Gram positive organisms in 5 (3%). In 64 (40%) cases, no pathogen was isolated. In bacteria, Klebsiella spp. was isolated in 15 cases, Pseudomonas in 5 cases,…
Read the paper
Related studies
- Severe clinical outcomes of COVID-19 associated with proton pump inhibitors: a nationwide cohort study with propensity score matching
- Levofloxacin-Induced Tendon Rupture: A Case Report and Review of the Literature
- Association between cord blood 25-hydroxyvitamin D concentrations and respiratory tract infections in the first 6 months of age in a Korean population: a birth cohort study (COCOA)
- Neuroprotective Effects of Epicatechin against Oxidative Stress-Induced Cognitive Impairment: A Systematic Review and Meta-Analysis
- Quality evaluation and in vitro interaction studies between levofloxacin 250mg and diclofenac sodium 50mg tablets
- Molecular Epidemiology of mcr-1 -Positive Polymyxin B-Resistant Escherichia coli Producing Extended-Spectrum β-Lactamase (ESBL) in a Tertiary Hospital in Shandong, China
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.