Evidence Hub

Early Rehabilitation in adult and paediatric critically ill patients with respiratory failure, sepsis, and pneumonia: Case series

Putri Alfaridy Lubis, S. C. Widjanantie, A. Paulus, T. E. T. Hasibuan, Ernita Akmal, Navy G. H. M. Lolong Wulung, Saad Chalid Badegesh, Hening Laswati Putra

Persahabatan Respirology Journal, 2026

Abstract

Background: Critically ill patients with acute respiratory failure,sepsis, pneumonia,and complex comorbidities frequently develop prolonged ventilator dependence,impaired airway clearance, intensive care unit-acquired weakness (ICU-AW), anda high risk oof post-intensive care syndrome (PICS). Early, structured rehabilitationthat integrates respiratory support, neuromuscular preservation, and mobilizationmay improve recovery.

Case: This case series describes three patients treated in the adult ICU andpediatric ICU of Persahabatan General Hospital's who received individualizedintensive rehabilitation. A young adult with obesity, type 2 diabetes and sepsis; amiddle-aged adult with severe community-acquired pneumonia and prolongedmechanical ventilation; and a preschool child with status epilepticus, sepsis, andbronchopneumonia. Functional status was evaluated using ICU Mobility Scale(IMS), Chelsea Critical Care Physical Assessment Tool (CPAx), Medical ResearchCouncil Sum Score (MRC-SS), Functional Status Scale (FSS), and grip strength.After 2 weeks, case 1 showed IMS improving from 0 to 6, CPAx from 2 to 27, andMRC-SS from 40 to 60, alongside successful ventilator weaning. After 3 weeks,case 2 showed CPAx improving from 5 to 20, IMS from 1 to 4, MRC-SS from 24to 32, grip strength from 5.2 to 11.3 kg in both arms, and cough flow from 45 to 79L/min. Case 3 showed FSS improving from 23/36 to 16/36 and IMS from 0 to 6after 3 weeks.

Discussion: These cases illustrate the feasibility…

How strong is the evidence?

Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free