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Combination eravacycline therapy for ventilator‐associated pneumonia due to carbapenem‐resistant Acinetobacter baumannii in patients with COVID‐19: A case series

Melissa N W Jackson, Wenjing Wei, Norman S. Mang, Bonnie C. Prokesch, J. Ortwine

Pharmacotherapy, 2024

24 citations

Abstract

Carbapenem‐resistant Acinetobacter baumannii (CRAB) pneumonia is associated with poor clinical outcomes and increased mortality. Clinical data regarding the optimal treatment of CRAB is limited, and combination therapy is often preferred. Eravacycline has demonstrated in‐vitro activity against A. baumannii and has been considered for the treatment of pulmonary infections caused by CRAB.

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Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

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