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A Retrospective Case Series Study of Alcaligenes faecalis Pneumonia

Chienhsiu Huang

Jundishapur Journal of Microbiology, 2024

Abstract

Background: The potentially developing human pathogen Alcaligenes faecalis is a gram-negative, nonfermenting bacterium. Treatment of A. faecalis infections is frequently difficult due to increased resistance to many antibiotics, such as β-lactam antibiotics, aminoglycosides, and quinolones. In the literature, A. faecalis pneumonia has never been documented in a case series study. Here, we provide a case series study of patients with A. faecalis pneumonia. Objectives: The aim of this study was to elucidate the clinical characteristics, management strategies, and outcomes of A. faecalis pneumonia patients. Methods: Patients with A. faecalis pneumonia between January 2014 and December 2019 were included in a retrospective investigation. We examined the clinical outcomes of patients with A. faecalis pneumonia, together with the risk factors for pneumonia, prior intravenous antibiotic use within 90 days, respiratory secretion culture results, antibiotic sensitivity test results, and other variables. Results: Observations revealed eight patients with A. faecalis pneumonia, including six males and two females. The mean age of patients was 70 years. These eight patients shared risk factors for pneumonia. Six patients were discharged, and two patients died as a result of A. faecalis pneumonia. Two patients with pneumonia caused by extensively drug-resistant A. faecalis were identified. Conclusions: Rare cases of A. faecalis pneumonia have been documented in the literature. Recently,…

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Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

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