Was the occurrence of mycoplasma pneumoniae pneumonia combined with cerebral watershed infarction a coincidence?: A CARE compliant case series and literature review
Abstract
Rationale: Mycoplasma pneumoniae (MP) is one of the most common respiratory pathogens in children. The prevalence of MP-induced pneumonia (MPP) has increased significantly in China since the outbreak of pediatric respiratory diseases in 2023. MP can affect almost every organ system in the body. The incidence of cerebral infarction in MPP is relatively rare, and the mechanisms involved in the occurrence of MPP with cerebral infarction are not completely clear. Patient concerns: The clinical data of children with MPP admitted to Hebei Children’s Hospital between January 2018 and January 2024 who developed cerebral infarction during the acute stage were reviewed. Cerebral magnetic resonance imaging revealed cerebral watershed infarction in all 4 children included in the study. The thrombi were detected in other arteries in Cases 1 and case 4, and both of them tested positive for MP-PCR in their cerebrospinal fluid. Cases 2 and case 3 underwent fibrebronchoscopy under basic anesthesia and developed hemiplegia 2 hours and 1 day postoperatively, respectively. Diagnoses: Based on the clinical manifestations and laboratory test results, 4 patients could be diagnosed with MPP. These children exhibited positive neurological symptoms during the acute stage of pneumonia, considering the characteristics of the brain magnetic resonance imaging, cerebral watershed infarction can be diagnosed simultaneously. Interventions: Patient 1 and 3 received urokinase thrombolytic therapy, and was…
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