Topical Application of Magnetized Saline Water Hydrogel Promotes Rapid Pressure Ulcer Healing in Hospitalized Elderly Patients: An Acute Care Case Series
Abstract
Pressure ulcers, particularly among elderly patients with acute medical conditions, represent a significant clinical challenge and are associated with substantial morbidity and healthcare resource utilization. Autophagy, a fundamental cellular pathway involved in protein and organelle degradation, has emerged as a critical regulator of tissue repair and wound healing by orchestrating inflammatory cell activation, extracellular matrix deposition, and keratinocyte proliferation and differentiation. Topical application of magnetized saline water (MSW) may increase the expression of autophagy biomarkers in skin tissue, representing a potentially efficacious management strategy for wound care. We conducted a prospective observational case series to explore the clinical utility of a topical hydrogel containing 95% MSW in the management of stage 2‒3 pressure ulcers in elderly patients admitted to an acute medical unit. Five geriatric inpatients (age range: 75-93 years) who developed hospital-acquired pressure ulcers during acute care hospitalization were included in the study. Following standard wound cleaning protocols, the topical MSW hydrogel was applied daily to the affected areas. Wound healing progression was monitored via clinical photography, assessment of granulation tissue formation, and documentation of any adverse events. All patients exhibited effective wound healing, with clear clinical improvement observed as early as three days and up to 10 days following initiation…
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Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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