Subsurface bioimaging using angular domain optical backscattering illumination
Abstract
While coherence or time domain optical tomography within highly scattering media observes the shortest path photons over the dominant randomly scattered background light, backscattering angular domain imaging employs micromachined collimators to detect photons within small angles of laser light reflected from the high scattering medium. These angular filters are composed of micromachined semicircular silicon collimator channels. By illuminating from the front side phantom test objects were observed in scattering media up to 3 mm deep in the medium at effective scattered to ballistic ratios from 1:1 to greater than 3E12:1. Results from carbon coating the collimators using a sputtering system to decrease internal reflectivity are shown.
Read the paper
Related studies
- Description and dosimetric verification of the PEREGRINE Monte Carlo dose calculation system for photon beams incident on a water phantom
- Fast Monte Carlo based joint iterative reconstruction for simultaneous 99mTc/ 123I SPECT imaging
- Dual modality intravascular catheter system combining pulse-sampling fluorescence lifetime imaging and polarization-sensitive optical coherence tomography
- mmWaveCam: Human Vital Motion Imaging and Focused Vital Signs’ Sensing
- Task-based Design of a Synthetic-collimator SPECT System used for Small-animal Imaging
- Multicolor fluorescence microscopy for surgical guidance using a chip-scale imager with a low-NA fiber optic plate and a multi-bandpass interference filter
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.