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Diagnosis of Acute Myeloid Leukaemia Using Machine Learning

A. Angelakis, I. Soulioti

arXiv, 2021

2,177 participants

Abstract

We train a machine learning model on a dataset of 2177 individuals using as features 26 probe sets and their age in order to classify if someone has acute myeloid leukaemia or is healthy. The dataset is multicentric and consists of data from 27 organisations, 25 cities, 15 countries and 4 continents. The accuracy or our model is 99.94\% and its F1-score 0.9996. To the best of our knowledge the performance of our model is the best one in the literature, as regards the prediction of AML using similar or not data. Moreover, there has not been any bibliographic reference associated with acute myeloid leukaemia for the 26 probe sets we used as features in our model.

How strong is the evidence?

Evidence Hub reads this as a preprint, done in computer models (in silico), not in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health. Reported size: 2,177 participants or records.

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