Prevalence and Influencing Factors of Anxiety and Depression in Patients With Breast Cancer: A Meta-Analysis
Abstract
Background: Breast cancer (BC) patients shoulder considerable psychologicalstrain asthey traverse the illness trajectory. While anxiety and depression among this population have received substantial research attention, comprehensive global estimates that distinguish anxiety from depression remarkably scarce. Even more understudied is the systematic review of factors unique to each condition. Our meta-analysis was designed to redress these gaps by establishing worldwide pooled prevalence figures for both anxiety and depression among BC patients, alongside mapping their associated risk and protective influences.
Objective: This study aimed to obtain consolidated global estimates of anxiety and depression prevalence within BC populations, and to explore various risk and protective factors that shape these.
Methods: This systematic review and meta-analysis included cross-sectional and cohort studies from multiple databases reporting anxiety/depression prevalence in BC patients. Two investigators independently conducted study selection, data extraction, and quality assessment using the Newcastle-Ottawa Scale (NOS). A random-effects model pooled prevalence estimates; heterogeneity was explored via subgroup analysis and meta-regression. Publication bias was assessed with Egger's test and funnel plots.
Results: This meta-analysis included 32 studies comprising 21,507 BC patients. The pooled prevalence of anxiety was 35% (95% confidence intervals (CI): 30%-39%), and that of…
How strong is the evidence?
Evidence Hub reads this as a meta-analysis, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 21,507 participants or records.
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