Lower urinary tract symptoms after total and subtotal hysterectomy: results of a randomized controlled trial

Gimbel H, Zobbe V, Andersen BJ, Sørensen HC, Toftager-Larsen K, Sidenius K, Møller N, Madsen EM et al.

International urogynecology journal and pelvic floor dysfunction, 2005

319 participants

Abstract

The aim of this Danish multicenter trial was to compare the proportion of women with lower urinary tract symptoms after total abdominal hysterectomy (TAH) and subtotal abdominal hysterectomy (SAH) for benign uterine disorders. A total of 319 women were randomized to TAH (n = 158) or SAH (n = 161). Women were followed up for 1 year by strict data collection procedures, including postal questionnaires. Results were analyzed by intention-to-treat analyses. Urinary incontinence was found less often among TAH women than among SAH women. This was due to a larger reduction of the number of women with stress and urinary incontinence in the TAH group. No other differences were found between the two operation methods. The number of women with urinary incontinence and frequency was reduced from study entry for follow-up, while double/triple voiding was increased. Incontinent women had significantly lower quality of life scores than continent women

How strong is the evidence?

Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 319 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

Read the paper

• DOI
• PubMed
• Publisher page

Related studies

• Understanding the factors influencing fall armyworm (Spodoptera frugiperda J.E. Smith) damage in African smallholder maize fields and quantifying its impact on yield. A case study in Eastern Zimbabwe Crop Protection, 2019
• Alarming situation of emerging H5 and H7 avian influenza and effective control strategies Emerging Microbes and Infections, 2022
• Livestock and food security: vulnerability to population growth and climate change Global Change Biology, 2014
• Atmosphere–ocean oxygen and productivity dynamics during early animal radiations Proceedings of the National Academy of Sciences of the United States of America, 2019
• Characterization of the global distribution and diversified plasmid reservoirs of the colistin resistance gene mcr-9 Scientific Reports, 2020
• The global seroprevalence of Toxoplasma gondii in pigs: A systematic review and meta-analysis Veterinary parasitology, 2019

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free