Regional Variation in Childhood Leukemia Incidence Rate in China: A Secondary Data Analysis
Abstract
Childhood leukemia is a common childhood cancer globally, with incidence varying by region. In China, this variation may relate to environmental, socioeconomic, and healthcare factors, but lacks systematic analysis. Our study aimed to assess the incidence rate of childhood leukemia across different regions in China and explore relevant influencing factors. Data were sourced from the Cancer Incidence on Five Continents (CI5), XII Edition, and the International Wealth Index from Global Data Lab (GDL), with descriptive statistics, comparative analysis, correlation analysis, and Poisson regression analysis employed for the study. Results revealed variations in childhood leukemia incidence across Chinese regions, with the highest rate in the southern region and the lowest in the eastern region; sex (higher in males) and age group (higher in younger age groups) exerted significant effects on incidence, while the wealth index had a weak impact, and the Poisson regression model (McFadden R² = 0.093) showed limited explanatory power. The study concluded that sex and age group are key factors influencing childhood leukemia incidence, while the wealth index has a limited impact; regional differences in incidence may be associated with environmental pollution, uneven distribution of medical resources, and socioeconomic conditions.
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