Epidemiology, Distribution, Key Characteristics, and Challenges of Candidozyma auris (Formerly Candida auris): A Narrative Review With a Special Focus on Türkiye
Abstract
This narrative review summarizes the epidemiology, microbiological and clinical features, antifungal resistance, transmission dynamics, and public health significance of Candidozyma auris globally and with a focus on Türkiye. C. auris has emerged as an important fungal pathogen because of its capacity for healthcare-associated colonization, environmental persistence, biofilm formation, laboratory misidentification, and multidrug resistance. Available evidence suggests that its rapid global spread is related to environmental tolerance, skin colonization, interclade phenotypic differences, and antifungal resistance mechanisms. Reported cases from Türkiye further support the need for strengthened infection control and surveillance systems. It represents a significant nosocomial fungal threat that necessitates the simultaneous implementation of clinical management and public health responses. In addition, it has been observed that the dominant clade in Türkiye is Clade I, that early cases were misidentified due to laboratory method-related limitations, and that there are substantial variations in antifungal susceptibility even within the same case series.
Read the paper
Related studies
- Understanding the factors influencing fall armyworm (Spodoptera frugiperda J.E. Smith) damage in African smallholder maize fields and quantifying its impact on yield. A case study in Eastern Zimbabwe
- Alarming situation of emerging H5 and H7 avian influenza and effective control strategies
- Livestock and food security: vulnerability to population growth and climate change
- Atmosphere–ocean oxygen and productivity dynamics during early animal radiations
- Characterization of the global distribution and diversified plasmid reservoirs of the colistin resistance gene mcr-9
- The global seroprevalence of Toxoplasma gondii in pigs: A systematic review and meta-analysis
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.