Landscape of Liver Injury From Herbal and Dietary Supplements in Europe, Latin America, and Asia
Abstract
• Herbal and dietary supplement hepatotoxicity (HILI) is scarcely reported in Europe and has a particular signature of hepatocellular pattern of liver injury, female sex predominance, and a greater severity compared with drug-induced liver injury (DILI) because of conventional medications. • In Latin America, preliminary unpublished data suggest that the relative prevalence of HILI with regard to DILI is greater than in Europe and the signature is similar. • In Asian countries, HILI, showing a similar signature than in the other continents, is the first cause of hepatotoxicity, except in India, despite the wide use of Ayurvedic medicine, although case series are increasingly being reported.
Read the paper
Related studies
- Understanding the factors influencing fall armyworm (Spodoptera frugiperda J.E. Smith) damage in African smallholder maize fields and quantifying its impact on yield. A case study in Eastern Zimbabwe
- Alarming situation of emerging H5 and H7 avian influenza and effective control strategies
- Livestock and food security: vulnerability to population growth and climate change
- Atmosphere–ocean oxygen and productivity dynamics during early animal radiations
- Characterization of the global distribution and diversified plasmid reservoirs of the colistin resistance gene mcr-9
- The global seroprevalence of Toxoplasma gondii in pigs: A systematic review and meta-analysis
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.