Evidence Hub

Leptospirosis: case reports of an outbreak in Guyana

Liverpool J, Francis S, Liverpool CE, Dean GT, Mendez DD

Annals of tropical medicine and parasitology, 2008

Abstract

Although leptospirosis is a globally important zoonotic disease that affects humans on all continents, in both urban and rural areas, it often goes undiagnosed because its clinical manifestations are frequently non-specific. Even when leptospirosis is suspected, confirmation is made difficult by problems in isolating the causative organism in culture and by the low sensitivity of the available serological tests. Following torrential rains and flooding in January-February 2005, an outbreak of leptospirosis was suspected in Guyana, South America. Overall, 108 suspected cases presented at a medical post in the East Coast area of Guyana, and some of these cases are described in detail here. A better understanding of the clinical and paraclinical characteristics of leptospirosis should improve the recognition and appropriate treatment of the disease. Health education could reduce exposure, and physicians and primary healthcare workers could be made more aware of the signs and symptoms of leptospirosis.

How strong is the evidence?

Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free