Dermatofibrosarcoma Protuberans of the Breast: A Rare Case Report
Abstract
Introduction: Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue sarcoma that grows from the dermis and is most commonly found in the trunk and proximal extremities. It is characterized by frequent local recurrences and invasive growth. Despite its rarity, DFSP can occur in the breast. In this report, we describe the successful treatment of a rare case of DFSP of the breast that resulted in long-term disease-free survival.
Case presentation: A 43-year-old Syrian woman diagnosed with a right breast mass and underwent a lumpectomy, which revealed DFSP. Subsequent imaging studies and biopsies excluded metastatic disease. Over the following years, the patient developed several benign breast, axillary, uterine, and flank lesions. At 6-year follow-up, she had no signs of local recurrence or metastasis.
Conclusion: This case report highlights the importance of early diagnosis and appropriate management of DFSP, even in unusual locations such as the breast. Overall, 6 years follow-up remains essential to monitor for any recurrences.
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Understanding the factors influencing fall armyworm (Spodoptera frugiperda J.E. Smith) damage in African smallholder maize fields and quantifying its impact on yield. A case study in Eastern Zimbabwe
- Alarming situation of emerging H5 and H7 avian influenza and effective control strategies
- Livestock and food security: vulnerability to population growth and climate change
- Atmosphere–ocean oxygen and productivity dynamics during early animal radiations
- Characterization of the global distribution and diversified plasmid reservoirs of the colistin resistance gene mcr-9
- The global seroprevalence of Toxoplasma gondii in pigs: A systematic review and meta-analysis
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.