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Surgical Presentations of Eosinophilic Gastroenteritis: A Case Report

Faydi T, Shomaf M, Kadri M, Kadri A, Kadri K

Cureus, 2025

Abstract

Eosinophilic gastroenteritis (EGE) is a rare disorder characterized by eosinophilic infiltration of the gastrointestinal (GI) tract without any definitive cause of eosinophilia. It presents with various non-specific GI symptoms, depending on the affected site and layer of involvement, often leading to delayed diagnosis and treatment. While the primary treatment consists of oral corticosteroids, extreme cases may necessitate surgical intervention. We present a case of a 50-year-old female who arrived at the emergency department with a three-day history of vomiting, diffuse abdominal pain, and tachycardia. She underwent emergency surgery due to acute abdominal symptoms. Intraoperatively, a mass-like lesion was identified in the distal antrum of the stomach, causing pyloric narrowing. Histopathological examination confirmed EGE. The patient had previously undergone laparoscopic cholecystectomy and open appendectomy for abdominal pain, which we now believe were misdiagnosed as separate surgical pathologies when they were possibly early manifestations of EGE. After an extensive literature review, this may be the first reported case of EGE in Jordan and the first case requiring a surgical procedure in the country.

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