Kimura's Disease: A Case Report
Abstract
Kimura's disease (KD) is a rare, chronic, autoinflammatory condition of unknown etiology, typically involving lymphoid and/or extranodal tissues of the head and neck area, usually presenting with peripheral blood eosinophilia and elevated serum immunoglobulin E (IgE) levels. The clinical features of KD are often variable and nonspecific, overlapping with other hematologic conditions, leading to diagnostic challenges. We report a case of a 36-year-old female with no prior medical history who presented with bilateral cervical lymphadenopathy, nodular lesions in the scalp, and elevated IgE levels, diagnosed with KD. We present a scoping review of the literature focusing on mass-like presentations of the head and neck region, recording the demographics, the clinical manifestation, the histopathology, and imaging findings, as well as the treatment and the outcomes. This case report and literature review highlight the necessity of clinical awareness of this rare condition and emphasize the need for interdisciplinary collaboration in the diagnostic process.
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Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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