Efficacy of acupuncture for stroke-associated pneumonia: a systematic review and meta-analysis
Abstract
Objectives This study aims to systematically evaluate the efficacy of acupuncture on stroke-associated pneumonia (SAP). Methods English and Chinese databases were searched from their inception until 15 March 2024 to collect randomized controlled trials (RCTs). The risk of bias was assessed using Cochrane collaboration tools. RevMan 5.4.0 software was used to analyze the included studies, and the Grades of Recommendations, Assessment, Development, and Evaluation (GRADE) assessment was used to evaluate the quality of the study outcomes. Results 16 studies involving 1,125 patients were included in this meta-analysis. Compared with the control group, the results showed that acupuncture significantly improved the effective rate [RR = 1.20, 95% CI (1.13, 1.27), P < 0.00001] and reduced the level of white blood cells (WBC) [MD = −6.52, 95% CI (−8.31, −4.73), P < 0.00001], C reactive protein (CRP) [MD = −6.50, 95% CI (−9.97, −3.03), P = 0.0002], neutrophil percentage (Neu%) [MD = −6.66, 95% CI (−8.96, −4.36), P < 0.00001], and procalcitonin (PCT) [MD = −0.81, 95% CI (−1.21, −0.40), P < 0.0001]. Additionally, acupuncture therapy shortened the duration of coughing [MD = −3.22, 95% CI (−4.73, −1.72), P < 0.0001], duration until disappearance of rales [MD = −3.99, 95% CI (−6.44, −1.54), P = 0.001], and duration of antibiotic use [MD = −4.51, 95% CI (−5.46, −3.57), P < 0.00001]. It also reduced the clinical pulmonary infection score (CPIS) [MD = −1.71, 95% CI (−2.71, −0.71), P = 0.0008]…
How strong is the evidence?
Evidence Hub reads this as a meta-analysis, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 1,125 participants or records.
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