Simultaneous development of Guillain–Barre syndrome and bacterial meningitis as complications of pneumonia caused by Staphylococcus aureus: a case report
Abstract
Guillain–Barre syndrome is an acquired inflammatory polyradiculoneuropathy that often follows gastrointestinal infection. A review of available literature revealed only few cases where Guillain–Barre syndrome developed after different types of meningitis. Furthermore, there are isolated cases of Guillain–Barre syndrome combined with meningeal irritation. This is the first reported case of Guillain–Barre syndrome and bacterial meningitis occurring simultaneously as complications of community-acquired pneumonia. We report the case of a 77-year-old Ukrainian male patient who presented to the hospital with clinical symptoms of pneumonia. Over the next day, he developed clinical symptoms of acute symmetric ascending flaccid tetraparesis. A few days later, synkinesis-like movements appeared in the paralyzed lower limbs. Microbiological studies of the cerebrospinal fluid identified antibiotic-sensitive Staphylococcus aureus. The patient received treatment with intravenous immunoglobulin and combination antibacterial therapy. The patient was discharged with improvement. In this case, a potentially life-threatening condition, such as bacterial meningitis, was asymptomatic and clinically unrecognized. It is important to recognize atypical cases of Guillain–Barre syndrome to achieve early diagnosis and treatment.
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Severe clinical outcomes of COVID-19 associated with proton pump inhibitors: a nationwide cohort study with propensity score matching
- Levofloxacin-Induced Tendon Rupture: A Case Report and Review of the Literature
- Association between cord blood 25-hydroxyvitamin D concentrations and respiratory tract infections in the first 6 months of age in a Korean population: a birth cohort study (COCOA)
- Neuroprotective Effects of Epicatechin against Oxidative Stress-Induced Cognitive Impairment: A Systematic Review and Meta-Analysis
- Quality evaluation and in vitro interaction studies between levofloxacin 250mg and diclofenac sodium 50mg tablets
- Molecular Epidemiology of mcr-1 -Positive Polymyxin B-Resistant Escherichia coli Producing Extended-Spectrum β-Lactamase (ESBL) in a Tertiary Hospital in Shandong, China
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.