Observation of levofloxacin in the treatment of elderly diabetic patients with community-acquired pneumonia
Abstract
Objective To evaluate the safety and clinical effect of levofloxacin of 400 mg once a day in treating elderly diabetic patients with community-acquired pneumonia(CAP).Methods The comparative study was conducted with the experimental group using levofloxacin 400 mg/time,intravenous infusion once a day and with the control group using levofloxacin 200 mg/time,two times daily intravenous infusion,for the total course of treatment of 10~14 days.The measures included clinical efficacy and safety.Results A total of 74 cases of patients were selected and the data were available for clinical efficacy for 70 cases.Among them there were 36 in the experimental group and 34 in the control group.The group comparisons indicated that there were significant difference in terms of types of disease,clinical efficacy,recovery rate and the rate of bacterial clearance(P0.05).the results also showed there was no significant group difference in terms of days of treatment and the rate of adverse reactions(P0.05).Conclusion Use of levofloxacin of 400 mg once daily intravenously in treatment of elderly diabetic patients with community-acquired pneumonia has good clinical effect,few adverse reactions,and is well tolerated.
Read the paper
Related studies
- Severe clinical outcomes of COVID-19 associated with proton pump inhibitors: a nationwide cohort study with propensity score matching
- Penicillins for Treatment of Pneumococcal Pneumonia: Does In Vitro Resistance Really Matter?
- Thiophenes—Naturally Occurring Plant Metabolites: Biological Activities and In Silico Evaluation of Their Potential as Cathepsin D Inhibitors
- Inhalable Mannosylated Rifampicin–Curcumin Co-Loaded Nanomicelles with Enhanced In Vitro Antimicrobial Efficacy for an Optimized Pulmonary Tuberculosis Therapy
- Development and validation of microbial bioassay for quantification of Levofloxacin in pharmaceutical preparations
- Association between cord blood 25-hydroxyvitamin D concentrations and respiratory tract infections in the first 6 months of age in a Korean population: a birth cohort study (COCOA)
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.