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Bacterial Colonization of Silver‐Additive Ventilator Circuit in Patients Receiving Mechanical Ventilation: A Randomized Controlled Trial

Ke-Yun Chao, Wei-Lun Liu, Chao-Yu Chen, C. Su, Shih-Hsing Yang, Yu-Tzu Huang

Clinical Respiratory Journal, 2025

3 citations

Abstract

Mechanical ventilation is a significant risk factor for developing ventilator‐associated pneumonia. Although silver‐coated endotracheal tubes have been shown to reduce the bacterial burden, the efficacy of silver‐based ion additive ventilator circuits in reducing bacterial colonization remains unclear.

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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.

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