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High-Altitude Pulmonary Edema Management in a Special Operator

Rodriguez JO, Shumway D, Tubbs P, Leek M, Nettlow D

Journal of special operations medicine : a peer reviewed journal for SOF medical professionals, 2026

Abstract

This case report delves into the challenges in diagnosis and management of a 30-year-old Army Special Forces officer who experienced respiratory distress during high-altitude training in Nepal, where he gained 3,000m in elevation over 3 days. Notably, the patient was prophylactically treated with acetazolamide but did not receive nifedipine or tadalafil. At an elevation of 13,550 feet (4,130m), the patient developed classic high-altitude pulmonary edema (HAPE) symptoms as well as concomitant respiratory symptomatology of breathlessness and worsening productive cough. The complexity of this case lay in managing HAPE in a remote, resource-limited environment with a small rescue window. We analyze the treatment alternatives used and ones not used, such as the portable hyperbaric chamber, and emphasize the necessity for standard-ized HAPE prophylaxis in appropriate personnel to prevent disruption to mission and loss of operational capabilities.

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