Safety and Pharmacokinetic Interaction Study of Tadalafil and Dutasteride
Abstract
This is an open-label, two-arm, one-sequence, cross-over study to evaluate the safety and pharmacokinetic interaction after oral concomitant administration of tadalafil and dutasteride in healthy male volunteers.
Conditions: Benign Prostate Hyperplasia.
Primary outcome: Area Under Curve (AUC) of tadalafil; Cmax of tadalafil; Area Under Curve (AUC) of dutasteride; Cmax of dutasteride.
Enrollment: 47 participants.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 47 participants or records.
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