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Tadalafil in Primary Pulmonary Arterial Hypertension

Emiliano A. Palmieri, Flora Affuso, Sergio Fazio, Danilo Lembo

Annals of Internal Medicine, 2004

46 citations

Abstract

Letters2 November 2004Tadalafil in Primary Pulmonary Arterial HypertensionEmiliano Antonio Palmieri, MD, Flora Affuso, MD, Serafino Fazio, MD, and Danilo Lembo, MDEmiliano Antonio Palmieri, MDFrom University Federico II Medical School, 80131 Naples, Italy, and Eli Lilly, 50019 Florence, Italy., Flora Affuso, MDFrom University Federico II Medical School, 80131 Naples, Italy, and Eli Lilly, 50019 Florence, Italy., Serafino Fazio, MDFrom University Federico II Medical School, 80131 Naples, Italy, and Eli Lilly, 50019 Florence, Italy., and Danilo Lembo, MDFrom University Federico II Medical School, 80131 Naples, Italy, and Eli Lilly, 50019 Florence, Italy.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-141-9-200411020-00033 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Background: Sildenafil, a short-acting phosphodiesterase-5 inhibitor (1), is safe and may benefit patients with primary pulmonary arterial hypertension (2-8). However, it requires many daily administrations. We describe a patient with end-stage primary pulmonary arterial hypertension who improved while taking tadalafil, a long-acting phosphodiesterase-5 inhibitor (9).Case Report: A 72-year-old woman was hospitalized for progressive cardiopulmonary failure. Five years earlier, primary pulmonary arterial hypertension was diagnosed and the patient was hospitalized for hydropic…

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