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Arduous management in treatment of elderly patient with pulmonary arterial hypertension and cardiopulmonary comorbidities

Enomoto Y, Kusaka K, Sato K, Takeda K, Kawashima M, Morio Y

Respiratory medicine case reports, 2025

Abstract

Elderly patients with pulmonary arterial hypertension (PAH) exhibit distinct features and outcomes compared to classical patients. Cardiopulmonary comorbidities are common and likely contribute to the development of pulmonary hypertension (PH). However, solid evidence for treating elderly PAH patients with these comorbidities remains lacking, complicating management. We report a case of a 74-year-old male with PAH and cardiopulmonary comorbidities who responded transiently to initial combination therapy with pulmonary vasodilators.

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