Efficacy of low-intensity extracorporeal shock wave therapy for erectile dysfunction: updated meta-analysis of randomized trials
Abstract
Background: Low-intensity extracorporeal shockwave therapy (Li-ESWT) is proposed for the treatment of erectile dysfunction (ED).
Materials and methods: Randomized controlled trials (RCTs) that compared Li-ESWT with sham therapy in patients with vasculogenic ED were included. The International Index of Erectile Function - Erectile Function (IIEF-EF) domain score, increase in the Erection Hardness Score (EHS), and improvement in Sexual Encounter Profile (SEP) 2 and SEP-3 were assessed.
Results: This meta-analysis of 12 RCTs, including 882 men with vasculogenic ED, demonstrated a statistically significant improvement in IIEF-EF score (an improvement from baseline as well as MCID) and EHS (patients with EHS ≥ 3) following LI-ESWT compared to sham therapy.
Conclusion: The results support the role of Li-ESWT as a potential treatment for ED.
How strong is the evidence?
Evidence Hub reads this as a meta-analysis, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 882 participants or records.
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