PIH21 influence of concomitant diseases on the clinical response to treatment for erectile dysfunction
Abstract
used as both a profile and single score measure. LiSat-11 is a generic validated checklist for self-perceived satisfaction with life. A Finnish, age-matched male population cohort was used for comparison. RESULTS: A total of 194 patients provided data for analysis at baseline and outcome at 3 months. The changes observed (baseline to endpoint) were as follows: average usage of ED tablets per four weeks increased from 4.7 to 9.7, intercourse attempts from 6.4 to 10.6, and the success rate of intercourses from 79% to 92%. At baseline, the 15D score was higher for the study patients than for the comparator population (0.924 vs. 0.902). Nevertheless, significant improvement (baseline to endpoint) was reported on the 15D dimensions of mobility, depression, distress (all p < 0.01), and sexual activity (p < 0.001); and life in general (p < 0.05), leisure (p < 0.01), sexual life, family life, and partnership relation (all p < 0.001) domains of LiSat11. CONCLUSIONS: When patients switched from other oral ED medication to tadalafil, improvement was seen in 3 of 15 dimensions of 15D and in 5 out of 11 domains of LiSat-11, including the closeness items: sexual life, partnership relation, and family life.
How strong is the evidence?
Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 194 participants or records.
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