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Extracorporeal Life Support (ECLS) for Pulmonary Vein Stenosis Interventions

Tsoi SM, Keller RL, Sacks LD, Sebastian V, Datar SA, Smith MA, Boehme J, Fineman JR et al.

Pediatric cardiology, 2026

Abstract

Pediatric pulmonary vein stenosis (PVS) is associated with high morbidity and mortality. We describe a case series of pediatric patients with advanced multivessel PVS who underwent cardiac catheterization with veno-arterial extracorporeal life support (VA-ECLS) to prevent cardiac arrest around high-risk pulmonary vein angioplasty and/or stent placement. VA-ECLS provided hemodynamic and respiratory stabilization, allowing completion of technically complex interventions in critically-ill pediatric patients who may not have otherwise tolerated catheterization. Using VA-ECLS in this setting requires a thorough assessment of risks versus benefits and specific patient criteria for consideration. This series highlights the potential role of VA-ECLS as an adjunctive strategy during high-risk catheter-based interventions for pediatric PVS to improve quality of life and lengthen lifespan.

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Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

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