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Erectile Dysfunction and Peyronie's Disease Following a Severe Case of COVID-19: A Case Report

Qualkenbush E, Gibbs E, Baird B, Broderick G

Case reports in urology, 2025

Abstract

The COVID-19 pandemic affected millions worldwide. While mainly regarded as a respiratory process, there may be both direct and indirect urologic consequences that are sparsely discussed. This case report describes a patient with a severe COVID-19 infection resulting in a kidney and liver transplant. After recovery, the patient was found to have de novo erectile dysfunction and Peyronie's disease. We suspect the systemic inflammation and vasculopathy leading to liver and renal failure also caused severe atherosclerotic erectile dysfunction. Furthermore, the prone positioning likely represents an iatrogenic etiology of Peyronie's disease. This unique case demonstrates some important considerations from a men's health perspective when caring for patients following a severe COVID-19 infection.

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Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

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