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Clinical Updates in Pulmonary Hypertension

Diaz G, Lawrence A, Ossi J, Arungwa D, Weiss A, Virk HUH, Khawaja M, Krittanawong C

Reviews in cardiovascular medicine, 2026

Abstract

Pulmonary hypertension is a heterogeneous, progressive condition affecting pulmonary vasculature. Epidemiologic studies have highlighted underdiagnosis and persistent disparities in access to expert care, treatments, and outcomes. Biomarkers and imaging‑based phenotyping are enhancing early detection, while emerging technologies for monitoring and novel treatment targets show promise for a new horizon in individualized management of pulmonary hypertension. This review aims to summarize the epidemiology, pathogenesis, definitions, treatment, and future directions of pulmonary hypertension.

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