Response surface methodology for optimizing adsorption process parameters for tadalafil removal by raw eggshell
Abstract
Abstract Excessive discharge of pharmaceutical wastes into the surface water causes harmful effect on environment, so its removal has aroused much attention in recent years. This study investigated the potential of raw eggshell as a low cost adsorbent on the removal of tadalafil by adsorption experiments. Characterization of adsorbent was investigated using Fourier-transform infrared spectroscopy (FT-IR), scanning electron microscope (SEM) and X-ray diffraction (XRD). To comprehensively evaluate the independent and interacting effects of several process factors, such as pH, temperature, and amount of adsorbent, Box-Behnken design was used. According to results of variance analysis (ANOVA) it was concluded that the second-order model had strong statistical relevance and was characterized by a high coefficient of determination (R2) value. It was clear from the experimental results that as the pH level and adsorbent amount were raised, so was the removal efficiency. At pH 5, 25 °C, and 7.5 g/100 mL of adsorbent, the greatest removal efficiency of 72.9% was attained. Furthermore, the analysis of equilibrium data showed that, in comparison to the Langmuir isotherm model, the Freundlich isotherm model offered a better fit for dye removal. Furthermore, the adsorption kinetic was also evaluated and it was obtained the adsorption followed by pseudo second order model for the tadalafil removal onto eggshell.
Read the paper
Related studies
- Protective effects of tadalafil and N-acetyl cysteine therapy on cisplatin-induced testicular toxicity
- The Use of Generative AI for Scientific Literature Searches for Systematic Reviews: ChatGPT and Microsoft Bing AI Performance Evaluation
- Sildenafil as a Candidate Drug for Alzheimer’s Disease: Real-World Patient Data Observation and Mechanistic Observations from Patient-Induced Pluripotent Stem Cell-Derived Neurons
- Ozone-modified properties of pumpkin seed oil as anti-H. pylori, anticancer, anti-diabetic and anti-obesity agent
- Effectiveness of Low-Intensity Extracorporeal Shock Wave Therapy in Erectile Dysfunction: An Analysis of Sexual Function and Penile Hardness at Erection: An Umbrella Review
- Molecular Docking of Silymarin as a Ligand for Aromatase Enzyme and HIV-1 Reverse Transcriptase Using Molegro Virtual Docker
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.