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Analysis of antibacterial therapy of community-acquired pneumonia in the therapeutic department

K. I. Mukhametzyanova, D. S. Sazonova

Russian Journal for Personalized Medicine, 2025

152 participants

Abstract

Background. Currently, the proportion of pneumonia of mycoplasma etiology (24 %) is increasing in the structure of all laboratory-confirmed cases of community-acquired pneumonia, which requires adjustment of empirical antibiotic therapy, taking into account the current flora, to accelerate recovery and reduce the risk of complications. Objective: to analyze the case histories of patients with pneumonia from January 2024 to November 2024. Analyze antibiotic therapy. Materials and methods. A retrospective analysis of the case histories of patients with pneumonia who are in the therapeutic department from 01.01.2024 to 30.11.2024 was carried out, and the Spearman’s rank correlation coefficient was calculated. Results. To conduct the study, data from 187 case histories of patients with community-acquired pneumonia were collected and retrospectively analyzed. Women (57 %), young patients aged 18–44 years (42 %) and middle-aged patients 45–59 years (25 %) were more likely to get sick, the course of the disease was predominantly severe (95.7 %). Correlations were revealed: severe course in young/middle-aged (coefficient 0.935), smokers (0.572) and HIV-infected (human immunodeficiency virus) (0.857). Every second patient had damage to the lower lobe of the lungs. One in four has multilobular lung damage. In most cases, in 152 patients (81.2 percent), a combination of levofloxacin and ceftriaxone was used to treat pneumonia. This combination was effective in 143 patients (94 %), the…

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