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Quantum-edge synergy for dynamic acoustic compensation in ultrasound safety: a narrative review of tissue heterogeneity challenges

Hu B, Shi W, Xiong S, Li S, Wang K, Gong N

Frontiers in medical technology, 2026

Abstract

Background: Conventional ultrasound safety monitoring relies on the Mechanical Index (MI) and Thermal Index (TI), which lack tissue-specificity. Consequently, real-time safety profiling remains imprecise. Dynamic, tissue-specific corrections such as tissue perfusion rate (TPR) aim to address this limitation. This narrative review examines how integrating these corrections with quantum-cloud computational frameworks may enable enhanced safety and image quality in ultrasonic applications.

Objective: We assessed the potential of an integrated quantum-cloud framework to reduce ultrasound-related bioeffects without compromising image quality, compared to standard MI/TI monitoring in patients undergoing clinical ultrasound imaging.

Methods: A narrative synthesis of the eligible literature was performed, guided by thematic analysis frameworks. Quantitative outcomes were descriptively summarized with medians and ranges; formal meta-analysis was not conducted because heterogeneity in TPR measurement protocols, device manufacturers, and outcome definitions violated the commutability assumption required for statistical pooling.

Results: Qualitative synthesis indicated that tissue-specific, multi-parameter correction strategies were consistently associated with more conservative acoustic exposure and heightened safety awareness than static MI/TI monitoring alone, although the consistency and clinical magnitude of these benefits varied across anatomical applications and study designs.…

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