Contrast and quantum noise in single-exposure dual-energy thoracic imaging with photon-counting x-ray detectors
Abstract
Abstract Objective. Photon-counting x-ray detectors (PCDs) can produce dual-energy (DE) x-ray images of lung cancer in a single x-ray exposure. It is important to understand the factors that affect contrast, noise and the contrast-to-noise ratio (CNR). This study quantifies the dependence of CNR on tube voltage, energy threshold and patient thickness in single exposure, DE, bone-suppressed thoracic imaging with PCDs, and elucidates how the fundamental processes inherent in x-ray detection by PCDs contribute to CNR degradation. Approach. We modeled the DE CNR for five theoretical PCDs, ranging from an ideal PCD that detects every primary photon in the correct energy bin while rejecting all scattered radiation to a non-ideal PCD that suffers from charge-sharing and electronic noise, and detects scatter. CNR was computed as a function of tube voltage and high energy threshold for average and larger-than-average patients. Model predictions were compared with experimental data extracted from images acquired using a cadmium telluride (CdTe) PCD with two energy bins and analog charge summing for charge-sharing suppression. The imaging phantom simulated attenuation, scatter and contrast in lung nodule imaging. We quantified CNR improvements achievable with anti-correlated noise reduction (ACNR) and measured the range of exposure rates over which pulse pile-up is negligible. Main Results. The realistic model predicted overall trends observed in the experimental data. CNR improvements…
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