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Optically pumped magnetoencephalography in epilepsy

Vivekananda U, Mellor S, Tierney TM, Holmes N, Boto E, Leggett J, Roberts G, Hill RM et al.

Annals of clinical and translational neurology, 2020

47 citations

Abstract

We demonstrate the first use of Optically Pumped Magnetoencephalography (OP-MEG) in an epilepsy patient with unrestricted head movement. Current clinical MEG uses a traditional SQUID system, where sensors are cryogenically cooled and housed in a helmet in which the patient's head is fixed. Here, we use a different type of sensor (OPM), which operates at room temperature and can be placed directly on the patient's scalp, permitting free head movement. We performed OP-MEG recording in a patient with refractory focal epilepsy. OP-MEG-identified analogous interictal activity to scalp EEG, and source localized this activity to an appropriate brain region.

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