A Children's Oncology Group Physics Committee Report on IROC Site Credentialing and Patient Case Review Results
Abstract
PURPOSE
The Imaging and Radiation Oncology Core (IROC) works with the Children's Oncology Group (COG) to provide institutional credentialing and patient radiotherapy plan review for sites that enroll patients on COG clinical trials. COG protocols that include radiotherapy require specific site credentialing activities depending on the treatment technique that is allowed in the protocol. In addition, there are protocol-specific treatment planning guidelines for tumor coverage and normal tissue sparing that define not only protocol acceptable limits, but also variations in limits if deemed clinically necessary, as well as protocol deviations. With many institutions participating in COG protocols, credentialing activities ensure standards for radiotherapy equipment and delivery are met and individual patient case reviews ensure consistency in target delineation, tumor coverage, and normal tissue avoidance for each protocol. The purpose of this work is to provide a descriptive analysis of retrospective credentialing and case review data for COG clinical trials.
METHODS AND MATERIALS
This work was conducted by representatives of the COG Physics Committee and aimed to characterize protocol deviations of recently closed COG trials. This analysis included closed COG protocols from a 10-year period (2013 to 2023). Phantom credentialing performance of COG institutions was assessed and compared to case review deviations to determine trends. Credentialing phantom irradiation failures…
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