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A Quantum Mixed-State Self-Harnessing Physics-Guided Neural Networks with Dandelion Optimizer Model for Breast Cancer Detection Using Histopathological Image

Karthikeyan Tangavelou

Frontiers in Engineering and Informatics, 2025

Abstract

Breast cancer is one of the common and life-threatening disorders in the world, as it requires proper and timely diagnosis to enhance the survival of the patient. Conventional diagnostic tools tend to be unable to evaluate high-dimensional histopathological image data, and the data is misclassified, which can lead to delayed treatment. To overcome this, the Quantum Mixed-State Self-Harnessing Physics-Guided Neural Networks with Dandelion Optimizer (QM-SS-HP-GNN-DO) is suggested to provide effective breast cancer diagnosis. To begin with, the images obtained and used in histopathology are gathered and preprocessed by Trainable Self-Guided Filtering (T-SGF) to improve the features of interest included in the BreakHis dataset. QM-SS-HP-GNN model subsequently provides classification, and Dandelion Optimizer (DO) optimizes the network weights to enhance the accuracy of the network. Experimental performance is better with an accuracy of 99.43%, precision of 99.10%, sensitivity of 99.05%, specificity of 99.20%, and F1-score of 99.08%, showing the best results compared to existing models. Overall, the suggested model offers a well-constructed, stable, and extremely precise framework of breast cancer diagnosis, and can be adapted to other medical image-based disease detection problems.

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