Nanotechnology and surgical neurology
Abstract
Sir,
Nanotechnology can be defined as the science and engineering involved in the design, synthesis, characterization, and application of materials and devices whose smallest functional organization, in at least one dimension, is on the nanometer scale or one billionth of a meter, and the promise that nanotechnology brings is multifaceted, not only offering improvements to the current techniques but also providing entirely new tools and capabilities.[3] Nanotechnology as a science has evolved from notions and speculation to emerge as a prominent combination of science and engineering, which stands to impact innumerable aspects of technology.[2] Various nanotechniques will make substantial contributions to the advancement of neurosurgery in the near future, such as (1) nanomanipulation, (2) nanoimaging, (3) non-surgical nanorepair, and (4) nanoneuromodulation. Nanomanipulation includes several techniques for performing what might be called “surgery” on the nervous system at the level of the neuron, neuronal processes, or intracellularly. Nanoimaging refers to viewing the nervous system (and its disorders) at the cellular or subcellular level. Non-surgical nanorepair considers substances (usually manufactured rather than naturally occurring) with impressive properties to promote axonal regeneration, halt deleterious processes (e.g., hemorrhaging), and extend neuronal (and organ to organism level) lifespan. Nanoneuromodulation refers to interacting with the nervous system at…
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