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Optical neuromodulation at all scales: from nanomaterials to wireless optoelectronics and integrated systems

Onuralp Karatum, Min-Jun Gwak, Junghun Hyun, Asım Önal, Gyan Raj Koirala, Tae‐il Kim, Sedat Nizamoğlu

Chemical Society Reviews, 2023

53 citations

Abstract

, nanotransducers and microphotodiodes. Then, we review the use of organic and inorganic light-emitting diodes for optogenetics and implantable wireless optoelectronic systems that enable closed-loop optogenetic neuromodulation through the use of light-emitting diodes, wireless power transfer circuits, and feedback loops. Exploration of materials and mechanisms together with the presented applications from both research and clinical perspectives in this review provides a comprehensive understanding of the optical neuromodulation field with its advantages and challenges to build superior systems in the future.

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