Impact of Drug Delivery Systems on Radiological Imaging Quality; A Comparative Analysis Through Systematic Review
Abstract
Background: Smart, or controlled release systems are one of the major developments in pharmacology which has the potential of improving the efficacy of a drug while reducing the toxic impact it has on the rest of the body. These systems include all the nano-technological strategies and controlled release strategies targeted at delivering drugs to the tissues. Aim: Verify and quantify the effects of different drug delivery systems throughout the quality of radiological imaging. Thus, the study aims to determine the most useful strategies referring to the improvement of the contrast, Method: From PubMed, Scopus, and Web of Science databases starting from 2019 to 2024, an electronic search yielded 6858 articles, out of which only relevant English articles were considered. The search criteria included articles and reviews concerning advanced drug delivery system, while exclusion factors were low methodological quality of the studies and articles published in languages other than English. In total, 8 papers were identified that met the criteria for further qualitative analysis, which creates a reasonable and strong foundation for the synthesis of the developments in question. Results: Evidently, progressive nanocarriers and SDDS were established to improve significantly the quality of radiological imaging over conventional DDS. Liposomes, micelles, and quantum dots, which are examples of nanocarriers, as well as SDDS, exhibited enhanced targeting precision, increased…
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Evidence Hub reads this as a systematic review. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.
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