In Silico Evaluation of Light Irradiation in Photodynamic Therapy for Peripheral Lung Cancer
Abstract
呼吸器領域における光線力学治療（photodynamic therapy: PDT）では狭隘な空間にて適切な光照射が求められる．光照射条件の解析には組織内光伝搬計算機シミュレーションに基づくin silico評価が有効となる．本稿では，末梢型肺癌を対象にして，モンテカルロ法に基づく組織内光伝搬の計算機シミュレーション方法，PDT光照射プローブの性能評価，術前治療評価に向けた臨床画像データに基づく光照射条件評価について，著者らの研究を中心に紹介する．
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