Ridge preservation in molar sites comparing xenograft versus mineralized freeze-dried bone allograft: a randomized clinical trial."
Abstract
OBJECTIVES
To compare the dimensional ridge changes and the histological composition after the use of an allograft or xenograft and a resorbable membrane in ridge preservation in molar sites, and to evaluate the influence of bone plate thickness on dimensional changes and the need of lateral sinus augmentation following ridge preservation.
MATERIAL AND METHODS
Twenty-four patients in need of maxillary or mandibular first or second molar extraction and subsequent implant placement were included and randomly assigned to a group; allograft or xenograft, plus a collagen membrane. Cone Beam Computed Tomographies were obtained after molar extraction and after five months. A bone sample was harvested at the time of implant placement and analysed by histomorphometry.
RESULTS
Bone ridge was reduced significantly. Major changes in width occurred at 1 mm from the bone crest (-2.93 ± 2.28 mm) (p = 0.0002), while in height, the greatest reduction occurred at the buccal area (-1.97 ± 2.21 mm) (p = 0.0006). However, differences between groups were not significant. Thicker buccal bone plates exhibited less bone remodelling, while histologically, both biomaterials resulted in similar tissue composition. The resulting available bone height in the implant site measured 7.30 ± 3.53 mm initially and 6.8 ± 3.61 mm after 5 months which allowed implant placement without the need of lateral sinus augmentation in all cases. Still, 55% of the preserved areas needed transcrestal sinus lift.
CONCLUSION…
How strong is the evidence?
Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.
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