The use of multimodality imaging in heart transplant recipients: a case series
Abstract
Abstract Background Acute cardiac allograft rejection and cardiac allograft vasculopathy are among the most common and dreaded complications occurring after successful heart transplantation and mandate lifelong monitoring. Non-invasive cardiac imaging with cardiac computed tomography (CCT) and cardiovascular magnetic resonance (CMR) has the potential to reduce the number of invasive exams needed with patient and economic benefits. We present our experience with these imaging techniques in the care of heart transplant recipients. Case summary The first case is a 48-year-old man diagnosed with severe cardiac allograft vasculopathy and subacute asymptomatic anterior myocardial infarction with no residual viability at CMR, where CCT demonstrated complete recanalization of an occluded left anterior descending artery after intensified immunosuppressive therapy. The second case is a 57-year-old man presenting with cardiac arrest due to coronary artery spasm that caused transitory regional wall motion abnormalities subsequently documented with CMR and successfully treated with medical and interventional therapy, owing to the presence of a functionally-significant coronary stenosis possibly triggering vasospasm. The third case is a 69-year-old man hospitalized for acute allograft rejection and severe biventricular dysfunction where CMR was key in managing immunosuppression intensification, alongside endomyocardial biopsy, with complete normalization of biventricular function.…
How strong is the evidence?
Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- In silico toxicology protocols
- QM7-X, a comprehensive dataset of quantum-mechanical properties spanning the chemical space of small organic molecules
- Quantum Informed Machine-Learning Potentials for Molecular Dynamics Simulations of CO2's Chemisorption and Diffusion in Mg-MOF-74
- In-silico strategies in nano-drug design: Bridging nanomaterials and pharmacological applications
- mRNA codon optimization with quantum computers
- The computational power of the human brain
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.