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QD-filled micelles which combine SPECT and optical imaging with light-induced activation of a platinum(IV) prodrug for anticancer applications

Maldonado CR, Gómez-Blanco N, Jauregui-Osoro M, Brunton VG, Yate L, Mareque-Rivas JC

Chemical communications (Cambridge, England), 2013

Abstract

The fac-[(99m)Tc(OH2)3(CO)3](+) complex reacts with QD-filled micelles to create a bimodal SPECT-optical imaging probe which upon visible light irradiation generates cisplatin from an inert Pt(IV) prodrug.

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