Preliminary Investigations of Transcranial Electrical Stimulation Effects on Neurophysiology and Behavior
Abstract
The objective of this randomized, double-blind, sham-controlled, crossover study is to evaluate the effects of transcranial electrical stimulation (tES) on complex cognitive task performance in healthy adult volunteers.
The primary questions this study aims to answer are:
1. Does tES improve task performance, including speed, accuracy, and overall success, during a computerized track-and-capture task?
2. Do different stimulation targets produce differential effects on performance?
3. Are there short-term post-stimulation effects on task performance (up to 48 hours)?
Participants will:
1. Complete two testing sessions under either active or sham stimulation conditions.
2. Perform a complex operational task involving dual-hand controllers while undergoing tES or sham stimulation, and immediately after.
3. Return for follow-up task performance assessments at 24 and 48 hours post-stimulation to evaluate after-effects.
Conditions: Healthy, Brain Stimulation, Transcranial Direct Current Stimulation (tDCS), Cognition, Psychomotor Performance, Neurophysiology.
Primary outcome: ROBoT-r Task Performance Score (During Stimulation); ROBoT-r Task Performance Score (Post-Stimulation); ROBoT-r Task Performance Score (Post-Stimulation Follow-up).
Enrollment: 44 participants.
How strong is the evidence?
Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 44 participants or records.
Read the paper
Related studies
- Preliminary Toxicity Analysis of 3DCRT versus IMRT on the High Dose Arm of the RTOG 0126 Prostate Cancer Trial
- Adaptive Radiotherapy for Head and Neck Cancer: Initial Clinical Outcomes from a Prospective Trial
- American Association of Physicists in Medicine Task Group 263: Standardizing Nomenclatures in Radiation Oncology
- Motion Management Strategies and Technical Issues Associated with Stereotactic Body Radiotherapy of Thoracic and Upper Abdominal Tumors: A Review from NRG Oncology
- High-dose-rate interstitial brachytherapy as a monotherapy for localized prostate cancer: treatment description and preliminary results of a phase I/II clinical trial
- Highly efficient training, refinement, and validation of a knowledge-based plan quality control system for radiotherapy clinical trials
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.