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Application of artificial intelligence in colonoscopy imaging for polyp analysis-A systematic review

Amirmohammadi E, Shalbaf A, Esteki A, Sadeghi A, Moghadam AR, Moghtaderi M, Moghadam PK

Computer methods and programs in biomedicine, 2026

Abstract

The colon is a major component of the digestive system, so early detection of colorectal polyps is essential in preventing colorectal cancer, which is a leading cause of cancer-related death worldwide. While colonoscopy remains the gold standard for polyp detection, its diagnostic accuracy is highly operator-dependent. Recent advances in Deep Learning (DL), a branch of Artificial Intelligence (AI), have shown substantial potential to improve colonoscopy image analysis by enhancing the accuracy, consistency, and objectivity of polyp detection, segmentation, and classification. Artificial intelligence-based systems have significantly reduced inter-observer variability and increased diagnostic efficiency, ultimately transforming the landscape of colorectal lesion assessment. This survey provides a comprehensive and critical analysis of the current status of deep learning applications in colorectal polyp analysis. We systematically review state-of-the-art methodologies across various DL architectures-including Convolutional Neural Networks (CNNs), transformer-based models, and hybrid approaches-and examine their performance on publicly available benchmark datasets. Additionally, we highlight the strengths and limitations of existing techniques, explore the clinical relevance of AI-assisted tools, and identify prevailing challenges such as data imbalance, real-time deployment, and generalizability across diverse populations and colonoscopy devices. By consolidating key advances…

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