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A Fully-Printed Wearable Bandage-Based Electrochemical Sensor with pH Correction for Wound Infection Monitoring

Kanyawee Kaewpradub, Kornautchaya Veenuttranon, Husanai Jantapaso, P. Mittraparp-arthorn, Itthipon Jeerapan

Nano-Micro Letters, 2024

53 citations

Abstract

The first example of a flexible array capable of detecting pyocyanin, a bacterial virulence factor, while correcting dynamic pH fluctuations. Developed a screen-printable conductive nanocomposite ink for fabricating the pyocyanin sensor and utilized a polyaniline/carbon nanocomposite as a pH-sensitive film for the pH sensor. Customized inks are advantageous in terms of flexible printed sensing array integrated onto a bandage surface, capable of monitoring both pyocyanin and pH levels in wound exudate. The first example of a flexible array capable of detecting pyocyanin, a bacterial virulence factor, while correcting dynamic pH fluctuations. Developed a screen-printable conductive nanocomposite ink for fabricating the pyocyanin sensor and utilized a polyaniline/carbon nanocomposite as a pH-sensitive film for the pH sensor. Customized inks are advantageous in terms of flexible printed sensing array integrated onto a bandage surface, capable of monitoring both pyocyanin and pH levels in wound exudate. Wearable sensing systems have been designed to monitor health conditions in real-time by detecting analytes in human biofluids. Wound diagnosis remains challenging, necessitating suitable materials for high-performance wearable sensors to offer prompt feedback. Existing devices have limitations in measuring pH and the concentration of pH-dependent electroactive species simultaneously, which is crucial for obtaining a comprehensive understanding of wound status and optimizing…

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