Skin-interfaced sweat monitoring patch constructed by flexible microfluidic capillary pump and Cu-MOF sensitized electrochemical sensor
Abstract
The limitations of skin-interfaced sweat monitoring are mainly reflected in the effective collection of sweat and the high sensitivity of the detection. This work proposes a new type of sweat monitoring patch based on a flexible microfluidic chip fabricated by a capillary pump and a copper-based metal-based organic framework (Cu-MOF) sensitized electrochemical sensor. The sweat in the microchannel is driven by a capillary pump to ensure the smooth collection and transportation. The sweat collection channel adopts the ingenious design of wedge-shaped structure, which helps to spontaneously generate Laplacian forces to direct sweat to the detection area. The detection area combines upper and lower capillary pumps, which aim to improve the efficiency of sweat collection. The controllable preparation of Cu-MOF was realized by using a micro-mixer, and the glucose sensor was prepared with it as the probe. The Cu-MOF/PANI layered electrode was prepared, which effectively improved the sensitivity of glucose detection and achieved a significant detection limit of 2.84 μM in the concentration range of 0-1 mM. Sodium and potassium selective electrode were also integrated into a unified screen-printed electrode, and a portable electrochemical detection module, a Bluetooth transmission module, and a mobile phone receiving application were developed. The sweat monitoring patch shows potential in applications such as sports performance monitoring, healthcare, and personalized medicine,…
Read the paper
Related studies
- Nano Biosensors: Properties, applications and electrochemical techniques
- Electrochemically Synthesized MIP Sensors: Applications in Healthcare Diagnostics
- Toward a Harmonization for Using in situ Nutrient Sensors in the Marine Environment
- Electrochemical determination of rutin by using NiFe2O4 nanoparticles-loaded reduced graphene oxide
- Application of Polyoxometalate-based composites for sensor systems: A review
- Sensitive Electrochemical and Thermal Detection of Human Noroviruses Using Molecularly Imprinted Polymer Nanoparticles Generated against a Viral Target
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.